Hox dosage contributes to flight appendage morphology in Drosophila

oleh: Rachel Paul, Guillaume Giraud, Katrin Domsch, Marilyne Duffraisse, Frédéric Marmigère, Soumen Khan, Solene Vanderperre, Ingrid Lohmann, Robby Stoks, L. S. Shashidhara, Samir Merabet

Format: Article
Diterbitkan: Nature Portfolio 2021-05-01

Deskripsi

Here, the authors show that the Hox genes Antennapedia (Antp) and Ultrabithorax (Ubx) control flight appendage morphology in Drosophila. This role is dependent on a particular spatial expression profile and dosage, which was also found in evolutionary distant four-winged insect species.