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At present, the world is faced with the coronavirus disease-2019 (COVID-19) threat caused by another novel coronavirus, the severe acute respiratory syndrome coronavirus 2. A 29-year-old patient diagnosed with primary infertility had COVID-19. Temporary severe oligo-astheno-teratozoospermia was observed in the long term; however, permanent losses occurred in rapid progressive sperms. His total testosterone level and total motile sperm count were permanently reduced. Permanent reductions occurred in his testicular volumes. But semen analysis values before COVID-19 was observed again. Pregnancy with intra cytoplasmic sperm injection was achieved with a high fertilization rate.