SAM-VI riboswitch structure and signature for ligand discrimination

oleh: Aiai Sun, Catherina Gasser, Fudong Li, Hao Chen, Stefan Mair, Olga Krasheninina, Ronald Micura, Aiming Ren

Format: Article
Diterbitkan: Nature Portfolio 2019-12-01

Deskripsi

Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discrimination.