Genome mining unveils a class of ribosomal peptides with two amino termini
oleh: Hengqian Ren, Shravan R. Dommaraju, Chunshuai Huang, Haiyang Cui, Yuwei Pan, Marko Nesic, Lingyang Zhu, David Sarlah, Douglas A. Mitchell, Huimin Zhao
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
RiPP discovery has expanded the scope of post-translational modification chemistry, but genome mining of RiPP classes remains an unsolved challenge. Here, the authors employed bioinformatics and synthetic biology approaches to discover and characterize an unknown class of RiPPs, defined by an unusual amino-modified C-terminus.