Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
oleh: Eloi Coutant, Paul C. Young, Graeme Barker, Ai-Lan Lee
| Format: | Article |
|---|---|
| Diterbitkan: | Beilstein-Institut 2013-09-01 |
Deskripsi
A gold(I)-catalysed reaction of allylic alcohols and phenols produces chromans regioselectively via a one-pot Friedel–Crafts allylation/intramolecular hydroalkoxylation sequence. The reaction is mild, practical and tolerant of a wide variety of substituents on the phenol.