Find in Library

Background: Coronary artery disease has higher prevalence in India than the West. Studies suggest that vascular age of Asian Indians is older to their chronological age, making them more susceptible for the disease. Association between various factors involved in patients having coronary artery disease and their lipid profiles in rural India is not clear. Objectives: The study focuses on the prevalence and comparative analysis of dyslipidemia in the patient group with respect to demographic data and comorbid conditions. Patients and Methods: This was a retrospective study which analysed 957 patients' hospital record in whom angiography was done for their coronary artery disease in a rural south India. Results: Statistically significant data (P < 0.005) were found in case of total cholesterol levels, with a mean being elevated in age below 45 years (178 ± 46 mg/dl) as compared to age above 45 years (167 ± 48 mg/dl). The mean total cholesterol levels were greater (177 ± 49 mg/dl) in women as compared to men (166 ± 48 mg/dl) with P < 0.005. Hypertensive patients showed elevated levels of total cholesterol and triglycerides. Patients with diabetes had elevated triglyceride levels in general. Conclusion: Triglyceride levels might be playing an important role than total cholesterol in the pathophysiology of CAD and for atherogenesis, it is the presence of hypertension with a deranged lipid profile, more so with total cholesterol and triglycerides.