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The swallowing of foreign bodies is generally accidental among adult population; most common foreign bodies are food scraps and dentures. Foreign bodies that can pass through the ileocecal valve are removed by defecation unless the presence of an underlying cause of colonic obstruction. The impaction of a foreign body into the colonic wall and the formation of colonic obstruction is a rare condition which might mimic malignancy. Segmental colon resection was performed to a 45-year-old male due to unnoticed swallowing of a denture approximately 4 months ago that resulted in colonic obstruction mimicking colon cancer in splenic flexura. As this is a rare condition, we aimed to present this case report.