A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)

oleh: P. Lewis White, Jan Springer, Matt P. Wise, Hermann Einsele, Claudia Löffler, Michelle Seif, Sabrina Prommersberger, Matthijs Backx, Jürgen Löffler

Format: Article
Diterbitkan: MDPI AG 2022-01-01

Deskripsi

The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmonary aspergillosis (CAPA)), the pandemic places a significant number of patients at potential risk from secondary invasive fungal disease. We described a case of CAPA with substantial supporting mycological evidence, highlighting the need to employ strategic diagnostic algorithms and weighted definitions to improve the accuracy in diagnosing CAPA.