Chemotherapy and target therapy as neo-adjuvant approach for initially unresectable colorectal liver metastases
oleh: Luigi Rossi, Angelo Zullo, Federica Zoratto, Anselmo Papa, Martina Strudel, Maria Colonna, Silverio Tomao
| Format: | Article |
|---|---|
| Diterbitkan: | Frontiers Media S.A. 2012-06-01 |
Deskripsi
Although surgery is the most effective treatment for liver metastases in colorectal cancer patients, only 15-20% of these patients are suitable for a radical surgical approach, and metastases recurrence may occur at follow up. In the last decade, the use of pre-operative chemotherapy in combination with new biological drugs has been introduced. We reviewed data of neo-adjuvant chemotherapy strategies aimed at increasing the resection rate of liver metastases in colorectal cancer patients who were initially considered unresectable.