Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA

oleh: John Papp, A. Jeanine Abrams, Evelyn Nash, Alan R. Katz, Robert D. Kirkcaldy, Norman P. O’Connor, Pamela S. O’Brien, Derek H. Harauchi, Eloisa V. Maningas, Olusegun O. Soge, Ellen N. Kersh, Alan Komeya, Juval E. Tomas, Glenn M. Wasserman, Gail Y. Kunimoto, David L. Trees, A. Christian Whelen

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2017-05-01

Deskripsi

During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.