Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis
oleh: Igor Mandric, Tommer Schwarz, Arunabha Majumdar, Kangcheng Hou, Leah Briscoe, Richard Perez, Meena Subramaniam, Christoph Hafemeister, Rahul Satija, Chun Jimmie Ye, Bogdan Pasaniuc, Eran Halperin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
Single cell RNA-sequencing can be a powerful approach to characterizing cell composition in a population of cells but is thought to be too expensive for population-scale analyses. Here, the authors show how lower coverage of more samples can increase the power to detect cell-type-specific eQTL.