Cellular and molecular signatures of in vivo imaging measures of GABAergic neurotransmission in the human brain

oleh: Paulina Barbara Lukow, Daniel Martins, Mattia Veronese, Anthony Christopher Vernon, Philip McGuire, Federico Edoardo Turkheimer, Gemma Modinos

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

Molecular origin of GABA receptor PET tracer signal is probed by performing correlation studies using regional PET signal and gene expression levels of GABA receptors and inhibitory interneuron markers. The results provide insight in the application and interpretation of these GABA receptor PET tracers in clinical populations.