The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
oleh: Mahesh Lingaraju, Dennis Johnsen, Andreas Schlundt, Lukas M. Langer, Jérôme Basquin, Michael Sattler, Torben Heick Jensen, Sebastian Falk, Elena Conti
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-07-01 |
Deskripsi
The human RNA exosome contains a nuclear co-factor MTR4, which unwinds structural RNAs and recruits adaptors for different RNA processing and decay pathways. Here the authors uncover new variations of the arch-interacting motif (AIM) in NVL and ZCCHC8 and characterise their interaction with MTR4.