Cytoplasmic forces functionally reorganize nuclear condensates in oocytes

oleh: Adel Al Jord, Gaëlle Letort, Soline Chanet, Feng-Ching Tsai, Christophe Antoniewski, Adrien Eichmuller, Christelle Da Silva, Jean-René Huynh, Nir S. Gov, Raphaël Voituriez, Marie-Émilie Terret, Marie-Hélène Verlhac

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Cytoskeletal activity generates mechanical forces known to agitate and displace membrane-bound organelles in the cytoplasm. In oocytes, Al Jord et al. discover that these cytoplasmic forces functionally remodel nuclear RNA-processing condensates across scales for developmental success.