Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis
oleh: Yi-Yu Chen, Jing-Yu Ge, Si-Yuan Zhu, Zhi-Ming Shao, Ke-Da Yu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-02-01 |
Deskripsi
Copy number alterations are pivotal genetic events in triple-negative breast cancer. Here the authors show the amplification of ENSA at the 1q21.3 region promotes the progression of TNBC via up-regulation of cholesterol biosynthesis.