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Application of glucocorticoids in patients with novel coronavirus infection: From bench to bedside
oleh: Linwei Lu, Jianhua Huang, Xiaohong Deng, Xianjun Sun, Jingcheng Dong
Format: | Article |
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Diterbitkan: | World Scientific Publishing 2020-12-01 |
Deskripsi
Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors and clinical applications in COVID-19. Through reviewing the current literature, our aim is to have a deeper understanding of the mechanism of GCs and their clinical applications, so as to find possible ways to enhance their efficacy and reduce drug resistance or side effects.