4-{[5-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}-N-(4-cyanophenyl)piperazine-1-carboxamide
oleh: V. Vijayakumar, R. Venkat Ragavan, Hoong-Kun Fun, Wan-Sin Loh, M. Venkatesh
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2010-10-01 |
Deskripsi
In the title compound, C28H22ClFN6O2, the piperazine ring adopts a chair conformation and the least-squares plane through the four coplanar atoms forms dihedral angles of 69.37 (13) and 56.56 (12)°, respectively, with the pyrazole and cyanophenyl rings. The dihedral angles formed between the pyrazole and the attached fluoro- and chlorophenyl rings are 34.16 (10) and 73.27 (12)°, respectively. In the crystal, intermolecular N—H...O, C—H...N and C—H...O hydrogen bonds link the molecules into sheets parallel to the ac plane.