Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

gan: Alexander Belyy, Dorothée Raoux-Barbot, Cosmin Saveanu, Abdelkader Namane, Vasily Ogryzko, Lina Worpenberg, Violaine David, Veronique Henriot, Souad Fellous, Christien Merrifield, Elodie Assayag, Daniel Ladant, Louis Renault, Undine Mechold

Fformat: Article
Cyhoeddwyd: Nature Portfolio 2016-12-01

Disgrifiad

The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.