Find in Library

MicroRNA (miRNA) is the class of short non-coding RNA, about 21 nucleotides in length. In general, miRNA functions as the post translational regulation in eukaryotic cells. Regarding its typical characteristics, especially in several cancers, with two prominent properties, namely the circulating and the stability of miRNA in bio-fluid, the miRNA is noticed as the potential biomarker in prognosis and early diagnosis of cancer.In the current review, we aim to introduce the molecular, the characteristics and molecular mechanism of miRNA bio-synthesis, and the activities of miRNA. Moreover, we tend to analyse and apply them as the potential biomarker for cancer. This will be the prerequisite to understanding and developing the miRNA study in Vietnamese patients.