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Expected life-spans increase all over the world and in our clinical experience we see atherosclerotic vascular diseases and malignant neoplasms more commonly. Herein, we want to present a case with coexistence of acute myocardial infarction and new diagnosed rectum cancer. Close monitoring is essential in these patients however stent thrombosis can be seen and patient and relatives should be informed about the risks and possible treatment choices in a detailed way.