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Mice infected with 3000 oocysts of T. gondii orally and subcutaenously, showed symptoms like dullness, off-feed, loss of hair and corneal opacity. Grossly, liver and lungs showed mottling and haemorrhage, while in sections there were inflammation, necrosis and mononuclear cell infiltration in most of the organs. Tissue cysts were observed in the liver, lungs, mesentery and brain. Isolation experiments were successful in mice.