Mapping the perturbome network of cellular perturbations

oleh: Michael Caldera, Felix Müller, Isabel Kaltenbrunner, Marco P. Licciardello, Charles-Hugues Lardeau, Stefan Kubicek, Jörg Menche

Format: Article
Diterbitkan: Nature Portfolio 2019-11-01

Deskripsi

Our understanding of the mechanisms of drug interactions remains limited. Here the authors introduce a framework to study how complex cellular perturbations induced by different drugs affect each other in morphological feature space.