Theory of branching morphogenesis by local interactions and global guidance

oleh: Mehmet Can Uçar, Dmitrii Kamenev, Kazunori Sunadome, Dominik Fachet, Francois Lallemend, Igor Adameyko, Saida Hadjab, Edouard Hannezo

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Many organs and cells have complex tree-like morphologies, but how these patterns emerge during development from global guidance cues and local self-organization remains unclear. Here, the authors develop a theory for the influence of both factors and test it on neuronal branching data.