High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo

oleh: Claire S. Koechlein, Jeffrey R. Harris, Timothy K. Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus W. Covert, Tannishtha Reya

Format: Article
Diterbitkan: Nature Portfolio 2016-07-01

Deskripsi

It is difficult to image haematopoietic stem cells (HSC) in their niche. Here, the authors present a new high-throughput computational approach to visualise HSCs in vivoat a high spatial and temporal resolution and also use a Msi2-reporter to label endogenous HSCs and progenitors, enabling cell tracking