Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance
oleh: Yan-Ting Chen, Qi-Yuan Yang, Yun Hu, Xiang-Dong Liu, Jeanene M. de Avila, Mei-Jun Zhu, Peter W. Nathanielsz, Min Du
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Maternal obesity predisposes offspring to obesity and metabolic disorders through incompletely understood mechanisms. Here the authors report that Dio3os is an imprinted long-coding RNA that modulates brown adipose tissue development and obesity resistance in the offspring.