Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ
oleh: Roman I Koning, Josue Gomez-Blanco, Inara Akopjana, Javier Vargas, Andris Kazaks, Kaspars Tars, José María Carazo, Abraham J. Koster
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
MS2 is a single-stranded RNA bacteriophage that infects its host via adsorption to bacterial pili. Here the authors visualize the MS2 virion with asymmetric cryo-EM reconstruction, revealing that the genome of MS2 adopts a specific structure of asymmetrically distributed stem-loops connected to the capsid.