Bio-inspired iron-catalyzed oxidation of alkylarenes enables late-stage oxidation of complex methylarenes to arylaldehydes
oleh: Penghui Hu, Mingxi Tan, Lu Cheng, Hongyuan Zhao, Rui Feng, Wei-Jin Gu, Wei Han
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-06-01 |
Deskripsi
Oxidation of toluenes to benzaldehydes is usually accompanied by overoxidation products. Here, the authors report an iron-catalysed aerobic oxidation of methylarenes to benzaldehydes with high yields and selectivities, even in presence of boronic acid groups and in complex natural products and drugs.