First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh

oleh: S.K.P. Lau, A.K.L. Tsang, S. Shakeel Ahmed, M. Mahbub Alam, Z. Ahmed, P.-C. Wong, K.-Y. Yuen, P.C.Y. Woo

Format: Article
Diterbitkan: Elsevier 2016-05-01

Deskripsi

We report the complete genome sequences of a buffalo coronavirus (BufCoV HKU26) detected from the faecal samples of two domestic water buffaloes (Bubalus bubalis) in Bangladesh. They possessed 98–99% nucleotide identities to bovine coronavirus (BCoV) genomes, supporting BufCoV HKU26 as a member of Betacoronavirus 1. Nevertheless, BufCoV HKU26 possessed distinct accessory proteins between spike and envelope compared to BCoV. Sugar-binding residues in the N-terminal domain of S protein in BCoV are conserved in BufCoV HKU26.