lncRNA transcription induces meiotic recombination through chromatin remodelling in fission yeast
oleh: Satoshi Senmatsu, Ryuta Asada, Arisa Oda, Charles S. Hoffman, Kunihiro Ohta, Kouji Hirota
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Senmatsu et al. show that transcription of long-noncoding RNAs (lncRNA) previously identified in the fission yeast fbp1 gene and found to induce chromatin opening, also activates meiotic recombination by inducing local chromatin remodeling at a meiotic recombination hotspot. This study furthers our understanding of the connection between lncRNA transcription and DNA break activity in yeast meiosis.