Localization of adaptive variants in human genomes using averaged one-dependence estimation

oleh: Lauren Alpert Sugden, Elizabeth G. Atkinson, Annie P. Fischer, Stephen Rong, Brenna M. Henn, Sohini Ramachandran

Format: Article
Diterbitkan: Nature Portfolio 2018-02-01

Deskripsi

Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.