Persistent telomere cohesion protects aged cells from premature senescence
oleh: Kameron Azarm, Amit Bhardwaj, Eugenie Kim, Susan Smith
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-07-01 |
Deskripsi
Telomere function is regulated by the telomere repeat binding proteins TRF1 and TRF2. Here the authors show that decreased levels of TRF1 proteins at shortened telomeres in aged human cells results in persistent telomere cohesion, protecting from premature senescence.