Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma

oleh: Laura Yerly, Christine Pich-Bavastro, Jeremy Di Domizio, Tania Wyss, Stéphanie Tissot-Renaud, Michael Cangkrama, Michel Gilliet, Sabine Werner, François Kuonen

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

The role of reciprocal tumour-stroma interactions in tumour invasion remains poorly characterised. Here, single-cell and spatial transcriptomics identifies the cell populations and their transcriptional reprogramming contributing to the spatial organization of the basal cell carcinoma invasive niche.