Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization
oleh: Li Zhang, Zhimin Cui, Qianqian Li, Bo Wang, Yuanling Yu, Jiajing Wu, Jianhui Nie, Ruxia Ding, Haixin Wang, Yue Zhang, Shuo Liu, Zhihai Chen, Yaqing He, Xiaodong Su, Wenbo Xu, Weijin Huang, Youchun Wang
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
Li Zhang, Zhimin Cui, and Qianqian Li et al. compare the infectivity, host tropism, and antigenicity of 10 SARS-CoV-2 variants using a VSV-based pseudovirus system. Their results suggest that variants carrying E484K display the most significant reduction in sensitivity to neutralization, and may provide further insight into the development of relevant therapeutics for SARS-CoV-2 infection.