Generation of hydroxyl radical-activatable ratiometric near-infrared bimodal probes for early monitoring of tumor response to therapy
oleh: Luyan Wu, Yusuke Ishigaki, Wenhui Zeng, Takashi Harimoto, Baoli Yin, Yinghan Chen, Shiyi Liao, Yongchun Liu, Yidan Sun, Xiaobo Zhang, Ying Liu, Yong Liang, Pengfei Sun, Takanori Suzuki, Guosheng Song, Quli Fan, Deju Ye
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
The hydroxyl radical is generated during radiotherapy and ferroptosis and accurate imaging of this reactive oxygen species may permit the monitoring of response to therapy. Here, the authors develop a ratiometric probe for accurate imaging of hydroxyl radical generation in vivo.