Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria
oleh: Jessika Consuegra, Joël Gaffé, Richard E. Lenski, Thomas Hindré, Jeffrey E. Barrick, Olivier Tenaillon, Dominique Schneider
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
Insertion sequences (IS) are common mobile genetic elements in bacteria, but their effects on bacterial evolution are not well understood. Here, Consuegra and colleagues investigate the dynamics and fitness consequences of IS elements in E. coli over 50,000 generations.