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Generation of induced pluripotent stem cell line (FMCPGHi001-A) from a 25-year-old Chinese Han healthy male donor
oleh: Tao Wang, Wenjing Tang, Quan Zeng, Shuai Miao, Chenghui Pi, Yingji Li, Wen Yue, Shengyuan Yu
Format: | Article |
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Diterbitkan: | Elsevier 2022-04-01 |
Deskripsi
Peripheral blood mononuclear cells (PBMC) were donated by a healthy 25-year-old Han Chinese man and reprogrammed with human transcription factors (Oct4, Sox2, Klf4, and c-Myc) using CytoTuneâ„¢-iPS 2.0 Sendai Reprogramming Kit. The pluripotency was confirmed by pluripotency markers. The iPSC lines could be differentiated into three germ layers and be used as a control in drug development and studies on pathological mechanisms.