INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury

oleh: Barbara Calabrese, Steven L. Jones, Yoko Shiraishi-Yamaguchi, Michael Lingelbach, Uri Manor, Tatyana M. Svitkina, Henry N. Higgs, Andy Y. Shih, Shelley Halpain

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

Post injury cytoskeletal modifications in neurons are not fully understood. Here the authors describe a pro-survival actin cytoskeletal reorganization in neurons triggered during a model of ischemic stroke.