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How splicing confers treatment resistance in prostate cancer
oleh: Prathyusha Konda, Srinivas R Viswanathan
Format: | Article |
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Diterbitkan: | eLife Sciences Publications Ltd 2022-08-01 |
Deskripsi
A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.