How splicing confers treatment resistance in prostate cancer

oleh: Prathyusha Konda, Srinivas R Viswanathan

Format: Article
Diterbitkan: eLife Sciences Publications Ltd 2022-08-01

Deskripsi

A splice variant of the androgen receptor that drives prostate cancer resistance translocates into the nucleus using a different mechanism from the full-length receptor and exhibits distinct molecular properties once inside.