Efficient Synthesis of β-Enaminones and β-Enaminoesters Catalyzed by Gold (I)/Silver (I) under Solvent-Free Conditions

oleh: Chengjian Zhu, Ming Zhang, Ablimit Abdukader, Yong Fu

Format: Article
Diterbitkan: MDPI AG 2012-03-01

Deskripsi

An efficient method for the synthesis of β-enaminones and β-enaminoesters using a combination of [(PPh3)AuCl]/AgOTf as catalyst has been developed. The reaction between 1,3-dicarbonyl compounds and primary amines was carried out under solvent-free conditions with low catalyst loading in good to excellent yields at room temperature.