Enantioselective construction of ortho-sulfur- or nitrogen-substituted axially chiral biaryls and asymmetric synthesis of isoplagiochin D

oleh: He Yang, Wenjun Tang

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Ortho-heteroatom-substituted axially chiral biaryls are valuable structures in synthetic and medicinal chemistry. Here, the authors established an efficient synthesis of these chiral structures via asymmetric cross-coupling.