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In the quest of finding new drug leads with potential antibacterial and antiepileptic activities, synthesis of thiazolidinone derivatives 6(a–c) is reported which are obtained from 5-(4-chlorobenzylidine)-3-[4-(7-chloroquinoline-4-ylamino]propyl)-2-imino-thiazolidin-4-one derivatives by applying appropriate synthetic route. These compounds 6(a–c) were evaluated for antibacterial and antiepileptic activities. Compound 6a having good lipophilicity is found to be most active.