The Aerogen<sup>®</sup> Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin

oleh: Ronald H. Dallas, Jason K. Rains, Keith Wilder, William Humphrey, Shane J. Cross, Saad Ghafoor, Jessica N. Brazelton de Cardenas, Randall T. Hayden, Diego R. Hijano

Format: Article
Diterbitkan: MDPI AG 2020-11-01

Deskripsi

Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen<sup>®</sup>). We did not observe any adverse events with this method.