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Abstract Background The primary manifestation of COVID-19 infection was pulmonary involvement. However, it can also manifest as a cardiovascular problem. Methods We report a case of 82-year-old male COVID-19 patient who experienced atrioventricular (AV) conduction disturbance. Results The rhythm was degenerated from sinus rhythm to complete AV block. We observe dynamic AV node dysfunction associated with inflammatory response. His bundle pacing successfully captured distal His region. Conclusion The severe inflammatory response during COVID-19 infection might permanently damage cardiac conduction system resulted in a complete AV node block.