Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
oleh: Nathan H. Kipniss, P. C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-12-01 |
Deskripsi
G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.