Case Report: Mast cell anergy: absence of symptoms after accidental re-exposure to amoxicillin/clavulanic acid 3 days after anaphylaxis

oleh: Loris Guyénard, Loris Guyénard, Marie Tauber, Marie Tauber, Sophie Debord-Peguet, Sophie Debord-Peguet, Frédéric Berard, Frédéric Berard, Audrey Nosbaum, Audrey Nosbaum, Florence Hacard, Florence Hacard, Mariana Castells, Jean-François Nicolas, Jean-François Nicolas

Format: Article
Diterbitkan: Frontiers Media S.A. 2024-03-01

Deskripsi

Empty mast cell syndrome, also named post anaphylaxis mast cell anergy (PAMA), is a temporary state of loss of mast cell responsiveness after a severe immediate hypersensitivity reaction. In this study, we describe a case of PAMA after accidental re-exposure to amoxicillin in a patient who developed severe anaphylaxis to this drug three days earlier in the operating room. To our knowledge, this report is the second to document this phenomenon.