Immunological imprinting of the antibody response in COVID-19 patients

oleh: Teresa Aydillo, Alexander Rombauts, Daniel Stadlbauer, Sadaf Aslam, Gabriela Abelenda-Alonso, Alba Escalera, Fatima Amanat, Kaijun Jiang, Florian Krammer, Jordi Carratala, Adolfo GarcĂ­a-Sastre

Format: Article
Diterbitkan: Nature Portfolio 2021-06-01

Deskripsi

In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the induction of specific antibodies against SARS-CoV-2.