The interhemispheric CA1 circuit governs rapid generalisation but not fear memory

oleh: Heng Zhou, Gui-Jing Xiong, Liang Jing, Ning-Ning Song, De-Lin Pu, Xun Tang, Xiao-Bing He, Fu-Qiang Xu, Jing-Fei Huang, Ling-Jiang Li, Gal Richter-Levin, Rong-Rong Mao, Qi-Xin Zhou, Yu-Qiang Ding, Lin Xu

Format: Article
Diterbitkan: Nature Portfolio 2017-12-01

Deskripsi

Previous work has documented a slow form of memory generalization although a rapid one is demanded. Here the authors elucidate the role of the interhemispheric CA1-CA1 projection in a form of rapid generalization of contextual fear memory via gradual potentiation of these synapses over 24 h.