Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria

oleh: Isabella C. Hirako, Marco A. Ataide, Lucas Faustino, Patricia A. Assis, Elizabeth W. Sorensen, Hisashi Ueta, Natalia M. Araújo, Gustavo B. Menezes, Andrew D. Luster, Ricardo T. Gazzinelli

Format: Article
Diterbitkan: Nature Portfolio 2016-11-01

Deskripsi

Cerebral malaria is an often fatal complication ofPlasmodium infection involving accumulation of inflammatory leukocytes in the central nervous system. Here the authors map the development and trafficking of CCR5+ monocyte-derived dendritic cells from the spleen to the brains of Plasmodium bergheiANKA infected mice.