A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma
oleh: Mathias Seviiri, Matthew H. Law, Jue-Sheng Ong, Puya Gharahkhani, Pierre Fontanillas, The 23andMe Research Team, Catherine M. Olsen, David C. Whiteman, Stuart MacGregor
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-12-01 |
Deskripsi
Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common skin cancers and have genetic overlap. Here, the authors use a multi-trait genetic and phenotypic analysis to reveal susceptibility loci for BCC and SCC, and report an optimised polygenic risk score for risk stratification.