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The aim of this paper is study of the effects of multiple cross-section of Au nanowire on mechanical properties. Different cross-section models of Au nanowires including circular, hexagonal, pentagonal and rectangular were simulated by finite element modeling using ABAQUS. In this study, the bending technique was applied so that both ends of the model were clamped with mid-span under loading condition. The cross-sections had the length of 400 nm and the diameter of 40 nm, except the circular cross-section while the rest of the cross-sections had an equivalent diameter. Von Misses stresses distribution were used to define the stress distribution in the cross-section under loading condition, and elastic deformation was analyzed by the beam theory. The results disclosed that the circular and the rectangular models had highest and lowest strengths against plastic deformation, respectively.